Evaluation of Optical Sonography for Real-Time Breast Imaging and Biopsy Guidance
Abstract
Despite advances in complementary approaches to breast mammography, breast cancer remains a prevalent and devastating disease. Advances fail to provide real-time, large field-of-view, high-resolution approaches to breast imaging where early detection and subsequent management of the disease are primary targets. This study evaluated a promising approach to breast imaging and image guidance using Diffractive Ultrasound (DUS), developed by Advanced Imaging Technologies, Inc. Systematic methods were developed for evaluating modifications to prototypes aimed at improving DUS image quality and adaptations for breast imaging. Ten normal volunteers and ten from a diagnostic group were studied to resolve procedural aspects of image acquisition, obtain data for a range of breast sizes and types to more fully evaluate the strengths and weaknesses of the technology, examine the robustness of processing algorithms, and establish descriptors for image interpretation. The study indicates that DUS has strength in differentiating soft tissue structures, particularly in women with dense breast composition, and identifying boundaries where strong diffractive components are present. The simulated biopsy data collected indicate that physicians can be successful in acquiring targets. Results indicate that DUS has a high potential for detecting and differentiating breast lesions and shows promise in providing accurate, real-time biopsy guidance.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2002
- Accession Number
- ADB285857
Entities
People
- Barbara A. Fecht
- Patrick S. Jensen
Organizations
- United States Army Medical Research and Development Command