Integration of Digital Detectors into a Diffraction Enhanced Imaging System

Abstract

Images of calcifications embedded in breast tissue specimens have been obtained using a synchrotron based diffraction enhanced imaging (DEI) system and subsequently compared to images obtained using synchrotron-based radiography. Of the three specimens imaged, two contained calcifications associated with breast cancer and one was benign. The samples were imaged using 18 kev synchrotron radiation at the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory. The DEI images were obtained by placing a Silicon analyzer crystal tuned to the 333 plane in the beam path between the sample and the detector. Contrast of the calcifications is consistently higher in the DEI images when compared to the normal radiographs. This comparison, called the gain value, is the ratio of the peak contrast (or refraction contrast) to the conventional radiographic contrast. In all three specimens the gain values were consistently larger than one, indicating that image contrast using DEI is much higher than from conventional synchrotron-based radiography.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2002
Accession Number
ADB286247

Entities

People

  • Dale E. Sayers
  • Miklos Z. Kiss

Organizations

  • North Carolina State University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Analyzers
  • Biomedical Research
  • Breast Cancer
  • Carcinoma
  • Computer Programs
  • Detectors
  • Diffraction
  • Government Procurement
  • Governments
  • Light Sources
  • Neoplasms
  • North Carolina
  • Radiation
  • Radiography
  • Refraction
  • Synchrotron Radiation

Fields of Study

  • Physics

Readers

  • Image Processing and Computer Vision.
  • Oncology and Biomarker-Based Cancer Detection.
  • Pulsed Power and Plasma Physics.