A Model of Penetrating Traumatic Brain Injury Using an Air Inflation Technique

Abstract

This report describes a method for modeling penetrating traumatic brain injury (PTBI) caused by gunshot using rats as the subjects. The method will be an improvement over previously used techniques in that it is minimally invasive, humane and based on a mathematical approach that is founded on known ballistic biophysics. This technique specifically avoids using a fired projectile. The proposed use of this animal model should improve the understanding of the pathophysiology of penetrating traumatic brain injury.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2003
Accession Number
ADB292823

Entities

People

  • Edward Moshang

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Ammunition
  • Animal Structures
  • Biomedical Research
  • Brain
  • Brain Injuries
  • Cell Physiological Processes
  • Contractors
  • Contracts
  • Free Flight
  • Government Procurement
  • Governments
  • Mathematical Models
  • Models
  • Muzzle Velocity
  • Programmed Cell Death
  • Specifications
  • Surgery

Readers

  • Computational Modeling and Simulation
  • Technical Research and Report Writing.
  • Trauma or Military Medicine

Technology Areas

  • Biotechnology