Lethal Concentration of Phosgene for Dogs for 7-1/2 Minute Exposure
Abstract
Introduction: The object of the present work was to determine the lethal concentration of phosgene for dogs for an exposure of seven and one-half minutes. The lethal concentration is defined as the least amount of the toxic substance in a gas-air mixture which will produce th deaths, within 10 days, of a majority (66-2/3%) of the animals exposed to a given concentration over a definite period of time. It is expressed in milligrams of compound per liter of air. Summary: The least concentration which will cause a majority of deaths within a period of 10 days lies between 1.08 and 1.15 milligrams per liter. The average concentration for the six dogs within the range indicated is 1.1 milligrams per liter. Conclusions: The lethal concentration of phosgene for dogs after an exposure of 7-1/2 minutes may be placed at 1.1 milligrams per liter. This is the equivalent of 270.6 parts per million at 25 deg C and 760 millimeters barometric pressure.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 23, 1922
- Accession Number
- ADB955157
Entities
People
- May G. Witherspoon
- William M. Groesbeck