Phosgene: Median Lethal Concentrations for Mice: 2- and 30-Minute Exposures

Abstract

The object of project A 10.2 is to determine the toxicity of various substances in order to estimate their value as possible war agents. The object of the work described in this report was to determine the median lethal concentrations of phosgene for white mice for exposure periods of 2 and 30 minutes and an observation period of ten days. The work was done in order to secure additional data for comparison of the toxicity of cyanogen chloride, hydrocyanic acid and phosgene. Conclusions: 1. The median lethal concentration of phosgene for white mice, for an exposure period of 2 minutes and an observation period of ten days, is 2.35 mg/l, with an average deviation of 0.25 mg/l. 2. The median lethal concentration of phosgene for mice, for an exposure period of 30 minutes and an observation period of ten days, is 0.112 mg/l, with an average deviation of 0.016 mg/l.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 22, 1941
Accession Number
ADB957358

Entities

People

  • E. Bowden
  • J. Saldick
  • R. L. Ferguson
  • S. D. Silver

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Chemical Warfare
  • Chlorides
  • Cyanides
  • Equations
  • Granular Materials
  • Lung
  • Materials
  • Nitrogen Compounds
  • Observation
  • Peroxides
  • Phosgene
  • Silver Compounds
  • Toxicity
  • Two Dimensional

Fields of Study

  • Agricultural and Food sciences

Readers

  • Toxicology/Environmental Toxicology