Improved Process for Producing 8-NHR Quinolines.
Abstract
An improved process for producing 8-NHR quinolines from 8-aminoquinolines is disclosed. The process comprises reacting 8-aminoquinolines with a substituted alkyl halide in the presence of an amine having a boiling point of 80-90 C. The amine functions as an acid acceptor whereby the amine salt formed may be efficiently separated from the 8-NHR quinoline formed without expensive or time consuming purification steps. The reaction may be carried out in the presence of a solvent such as an alcohol. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 03, 1977
- Accession Number
- ADD003781
Entities
People
- Andrew J. Saggiamo
- Edward A. Nodiff
- Eugene H. Chen
Organizations
- United States Department of the Army