Sealing of Glass Ampoules.
Abstract
A method of sealing gas-filled glass ampules and the like to insure the closure of any microscopic channel existing between the outer and the inner surface thereof, and its product of manufacture is described. After the ampoule is filled and sealed, it and its contents are suitable for storing in ambient or low temperature, or for freezing, or freeze-drying. However, flame-sealing of the ampoules usually results in a small channel through the sealed tip. All typical flame-type sealing methods substantially close the ampoule but the microscopic channel still remains. The presence of the channel is undesirable since it permits gas exchange between the ampoule contents and the outside environment. Therefore, a polymeric coating of neoprene rubber dissolved in toluene or other suitable material is employed to seal the flame-sealed tips of the ampoules to assure closure of any existing channel. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 22, 1975
- Accession Number
- ADD003874
Entities
People
- Donald Greiff
- Hewlett E. Melton
Organizations
- United States Department of the Navy