Method of Making Lipid Tubules by a Cooling Process.
Abstract
Diacetylinic phosphocholines have distinctly different endothermic and exothermic transition temperatures. Lipid tubules are formed by hydrating a diacetylinic phosphocholine at a temperature above its endothermic transition temperature. The hydrated lipid is then cooled slowly to a formation temperature 1- to 10 C below the exothermic transition temperature to form tubule structures. The tubules structures can be polymerized to form permanent tubules. The tubules can be used in the same manner as a liposome vesicle or they can be metal coated for a variety of applications.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 29, 1988
- Accession Number
- ADD013696
Entities
People
- Joel M. Schur
- Paul E. Schoen
- Paul Yager
Organizations
- United States Department of the Navy