A Membrane Based Dot Immunoassay and Method of Use.

Abstract

Antigens or antibodies are detected using a novel membrane based immunoassay. Known antigens or antibodies which will form complexes with antigens/antibodies to be assayed are spot filtered with pressure through a membrane. The membrane, either by itself or attached to a base material as a test strip, is incubated with a test fluid. Consequently, the resulting antibody-antigen complex is incubated directly or after an intermediate anti-antibody incubation with enzyme conjugated immunoglobulin and exposed to substrate which produces a colored insoluble product if the test target is present. Patent applications. (aw)

Document Details

Document Type
Technical Report
Publication Date
Jan 30, 1989
Accession Number
ADD014505

Entities

People

  • John J. Oprandy

Organizations

  • United States Department of the Navy

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biomedical And Dental Materials
  • Films
  • Immunoassay
  • Immunoglobulins
  • Incubation
  • Materials
  • Membranes
  • Patent Applications
  • Patents
  • Polymeric Films
  • Specialty Uses Of Chemicals
  • Substrates

Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Molecular and Cellular Biochemistry