Polynucleotide Vaccine Protective Against Malaria, Methods of Protection and Vector for Delivering Polynucleotide Vaccines. N9
Abstract
This invention relates to polynucleotide vaccines protective against malaria, and a vector for construction of this and other polynucleotide vaccines. More particularly, this invention relates to vaccines composed of, at a minimum, nucleotides encoding one or more Plasmodium species proteins, and compositions and methods of providing protection against malaria with such a polynucleotide vaccine. Also, the invention includes a plasmid vector including a cytomegalovirus promotor for insertion of nucleotides encoding targets of protective immune responses.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 23, 1993
- Accession Number
- ADD016130
Entities
People
- Martha Sedegah
- Richard Hedstrom
- Stephen L. Hoffman
Organizations
- United States Department of the Navy