Decaying Radiolabelled Lymphocytes and Method of Using Same Background of the Invention.
Abstract
Decaying radiolabelled lymphocytes and a method of using same are disclosed. A radiolabelled T-cell lymphocyte including a T-cell containing a Beta-emitting isotope which decays to an alpha-emitting isotope is provided. Alternatively, the T-cell may contain a Beta-emitting isotope which decays one of an x-ray and gamma-emitting isotope. A therapeutic radioisotope treatment method includes the steps of removing a cancerous nodule containing T-cells from a mammal, introducing into the T-cells a Beta-emitting isotope which decays to an alpha-emitting isotope and infusing the T-cells containing the Beta-emitting isotope which decays to an alpha-emitting isotope into the mammal. As an alternative, the treatment method may introduce into the T-cells a Beta-emitting isotope which decays to an x-ray or gamma-emitting isotope. Then, according to the alternative method, after the radioactive T- cells are infused into the mammal, the patient is monitored with a radiation detector to determine the location of T-cells containing the isotopes.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 30, 1994
- Accession Number
- ADD017410
Entities
People
- George P. Chambers
Organizations
- United States Department of the Navy