Antiplatelet Effect of Dimethyl Sulfoxide, Barbiturates, and Methyl Prednisolone,

Abstract

Despite advances in instrumentation, suture materials, and operative techniques, thrombus formation at the anastomotic site in small vessels remains a major factor that compromises surgical results. Adjunctive pharmacological attempts to reduce thrombus formation intraoperatively have been studied, but the effectiveness of these agents remains to be established in microsurgery. The present study was undertaken to compare and evaluate the antiplatelet properties of dimethyl sulfoxide (DMSO), pentobarbital, and methyl prednisolone in altering the thrombotic response inflicted by surgical trauma.

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1983
Accession Number
ADP001849

Entities

People

  • Fernando G. Diaz
  • Manuel Dujovny
  • Nir Kossovsky
  • Ricardo Segal
  • Rodney Rozario

Organizations

  • Henry Ford Hospital

Tags

DTIC Thesaurus Topics

  • Behavior And Behavior Mechanisms
  • Behavioral Disciplines And Activities
  • Behavioral Sciences
  • Chemical Compounds
  • Cooperation
  • Group Dynamics
  • Instrumentation
  • Materials
  • Microsurgery
  • Sulfur Compounds

Fields of Study

  • Medicine

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Trauma Surgery or Emergency Medicine.