Dimethyl Sulfoxide Therapy Following Penetrating Brain Injury,

Abstract

Dimethyl sulfoxide (DMSO) has been shown to be effective therapy in models of cerebral infarction and trauma. It may provide a protective effect against mechanical disruption, as well as improve CBF and control intracranial pressure (ICP). We, therefore, decided to test this therapeutic agent in our gunshot wound model. In the present study, we have examined the effects of DMSO initiated 1 hour following trauma.

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1983
Accession Number
ADP001850

Entities

People

  • Frederick D. Brown
  • Lydia Johns
  • Sean Mullan

Organizations

  • University of Chicago

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Brain Diseases
  • Brain Injuries
  • Central Nervous System Diseases
  • Cerebrovascular Disorders
  • Diseases And Disorders
  • Nervous System Diseases
  • Sulfur Compounds
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Trauma Surgery or Emergency Medicine.