Dimethyl Sulfoxide and Other Therapies in Experimental Pressure-Induced Cerebral Focal Ischemia,

Abstract

In evaluating seven different therapies, DMSO appears to be most effective in attenuating neurobehavioral signs and histological responses to pressure-induced focal ischemia with the cerebral perfusion pressure lowered to 20 torr. It seems that free-radical scavenging may be the critical mechanism of action by DMSO.

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1983
Accession Number
ADP001852

Entities

People

  • Leonid Bunegin
  • Maurice S. Albin
  • Philip Helsel

Organizations

  • University of Texas Health Science Center at San Antonio

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Chemical Compounds
  • Diffusion
  • Free Radicals
  • Ischemia
  • Perfusion
  • Sulfur Compounds

Fields of Study

  • Psychology

Readers

  • Molecular Photonics/Laser Physics
  • Neurotrauma and Rehabilitation Medicine.
  • Toxicology/Environmental Toxicology