Nephrotoxicity of Hydrocarbon Propellants to Male, Fischer-344 Rats

Abstract

The purpose of this report is (1) describe pathologic changes in the kidneys of male rats following both short and long-term exposure to hydrocarbon propellants. (2) Outline agents which have produced renal disease in rats, and (3) discuss possible pathogenic mechanisms resulting in nephrotoxicity and carcinogenicity.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1983
Accession Number
ADP001983

Entities

People

  • Lucius L. Pitts
  • Richard H. Bruner

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Biomedical Research
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Ecotoxicology
  • Electron Microscopy
  • Epithelial Cells
  • Epithelium
  • Hydrocarbon Fuels
  • Kidney Diseases
  • Kidneys
  • Microscopes
  • Neoplasms
  • Tissues

Fields of Study

  • Physics

Readers

  • Aerospace Test and Evaluation
  • Molecular and Cellular Biology
  • Toxicology/Environmental Toxicology