HPLC (High Performance Liquid Chromotography) Optimization on a Low-Cost Microcomputer,

Abstract

We developed a High Performance Liquid Chromotography (HPLC) Optimization program to solve a three solvent, 2 to 15 peak system using a 32K microcomputer. Although other programs accomplish similar types of data reduction, we were interested in a computer code that was user friendly and did not require an expensive mainframe computer. The computer code can output to: an internal graphics display, an external plotter, or an external printer. One can choose to solve the following: graphs showing desired iso-resolution lines of two peaks, graphs showing overall resolution of all peaks, best solution composition to maximize overall peak resolution, or complete peak analysis at a given solution composition. We run the program on an HP-85 system. Because the program is written in less than 32K of BASIC, it should be easily adapted to other microcomputers (Apple, Commodore, etc.). We have verified the code experimentally. The code and matching experimental data will be discussed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1985
Accession Number
ADP004987

Entities

People

  • J. G. Carver
  • L. L. Lindsay
  • M. B. Coolidge
  • R. A. Wurzbach

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Air Force
  • Colorado
  • Computers
  • Computing Devices
  • Data Reduction
  • Experimental Data
  • Graphics
  • Mainframe Computers
  • Optimization
  • Personal Computers
  • Propellants
  • User Friendly

Readers

  • Analytical Chemistry
  • Computer Science.