Development of a Paradigm to Assess Nutritive and Biochemical Substances in Humans: A Preliminary Report on the Effects of Tyrosine upon Altitude- and Cold-Induced Stress Responses

Abstract

Tyrosine, a large neutral amino acid found in food, is the precursor for the catecholamine neurotransmitters dopamine and norepinephrine. Recent experiments have shown the behavior of animals given tyrosine is less impaired after stressful treatments than that of animals given placebo. Various environmental stressors are known to deplete central catecholamine stores and tyrosine's positive behavioral effects in animals are associated with reversal of this neurochemical deficit. Therefore, we investigated whether tyrosine administration would reduce adverse behavioral and physiological effects in humans induced by two combined environmental stressors, hypoxia and cold.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1987
Accession Number
ADP005658

Entities

People

  • B. L. Shukitt
  • H. R. Lieberman
  • L. E. Banderet
  • R. F. Goldman
  • R. P. Francesconi

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Altitude
  • Amino Acids
  • Brain
  • Catecholamines
  • Computer Programming
  • Computers
  • Databases
  • Ear
  • High Altitude
  • Information Processing
  • Information Science
  • Pattern Recognition
  • Psychotropic Drugs
  • Reaction Time
  • Sea Level
  • Statistical Analysis
  • Tranquilizing Agents

Fields of Study

  • Biology
  • Psychology

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.