Bandit Strategies for Ethical Sequential Allocation,

Abstract

The problem of allocating patients in a two treatment clinical trial with dichotomous response is considered. The trial goal is to determine the better treatment while incurring as few patient losses as possible. Several allocation rules are compared and it is found that bandit strategies perform well on both criteria in that they achieve nearly optimal power while keeping expected trial failures nearly minimal. The rules are also evaluated according to their computational complexity.

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1992
Accession Number
ADP007181

Entities

People

  • Janis P. Hardwick
  • Quentin F. Stout

Organizations

  • University of Michigan

Tags

DTIC Thesaurus Topics

  • Clinical Trials
  • Computational Complexity
  • Computer Science
  • Data Science
  • Engineering
  • Information Science
  • Mathematics
  • Statistics
  • Theoretical Computer Science

Readers

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