Molecular Determinants in the Delta Selectivity of Deltorphins,
Abstract
The deltorphins were discovered in frog skin by their cDNA sequences and the isolated natural peptides contained D-amino acid enantiomer at position 2. Recognition of high delta affinities and delta selectivities of these peptides led to the examination of the molecular determinants required for interaction with opioid receptors.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1992
- Accession Number
- ADP008342
Entities
People
- L. H. Lazarus
- R. Tomatis
- S. Salvadori
- W. E. Wilson
Organizations
- National Institute of Environmental Health Sciences