Calcium Binding of Acyclic Peptides: NMR and Computational Studies,
Abstract
Much insight has been obtained on Ca(2+)-binding proteins from studies on cyclic peptides as well as on relatively large linear peptides with sequences resembling the ion-binding regions of these proteins. With the aim of delineating the minimal conformational features required for Ca(2+) binding, we synthesized several short linear peptides and examined their interaction with Ca+ by CD, NMR and molecular modeling methods.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1992
- Accession Number
- ADP008371
Entities
People
- A. Saint Jean
- B. Cheesman
- V. S. Ananthanarayanan
Organizations
- McMaster University