A Series of Highly Selective Thrombin Inhibitors,
Abstract
Tripeptide aldehydes such as Boc-D-Phe-Pro-Arg-H exhibit potent direct inhibition of thrombin. We have evaluated the structural and conformational role of the amino acid residue in position one of Boc-D-Phe-Pro-Arg-H.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1992
- Accession Number
- ADP008543
Entities
People
- Charles S. Campbell
- Donetta S. Gifford-moore
- Gerald F. Smith
- Robert B. Rothenberger
- Robert T. Shuman