Hr-Antihistamines and Aircrew

Abstract

For many years it was accepted that antihistamines were among the safest medications in the world, and this reputation was enhanced by the development of the so-called second generation compounds, which were largely free of adverse effects on vigilance and performance. It was against this background that there was wide agreement that they could be used safely by air crew. However, cardiotoxicity has now become an issue with these antihistamines, and the confidence which was once placed in their use for aircrew requires re-examination.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2001
Accession Number
ADP011043

Entities

People

  • Anthony N. Nicholson
  • Barbara M. Stone
  • Jeb S. Pickard
  • Ronald A. Davidson

Organizations

  • Department of National Defence

Tags

DTIC Thesaurus Topics

  • Cardiac Arrhythmias
  • Cardiovascular Diagnostic Techniques
  • Cardiovascular System
  • Diseases And Disorders
  • Health Services
  • Heart Diseases
  • Human Performance Tests
  • Hypnotics And Sedatives
  • Intervals
  • Metabolism
  • Metabolites
  • Motor Skills
  • Myocardial Ischemia
  • Performance Tests
  • Psychomotor Performance
  • Technical Information Centers
  • Test And Evaluation

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Strategic Security Studies
  • Toxicology/Environmental Toxicology