Losartan Potassium: A Review of Its Suitability for Use in Military Aircrew

Abstract

The renin-angiotensin system (RAS) plays a central role in the control of blood pressure, and in particular it is felt to play a crucial role in neurogenic hypertension. The RAS appears to act through two mechanisms, affecting the acute control of blood pressure through the pressor action of angiotensin II, and the long-term regulation of cardiovascular remodeling through the growth factor properties of angiotensin II.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2001
Accession Number
ADP011054

Entities

People

  • Jeb S. Pickard

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Blood
  • Blood-Brain Barrier
  • Brain
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Catecholamines
  • Central Nervous System
  • Heart Diseases
  • Hypertension
  • Inhibition
  • Inhibitors
  • Metabolism
  • Metabolites
  • Nervous System
  • Vascular Diseases

Readers

  • Cardiovascular Physiology
  • Molecular and Cellular Biology