In Vivo, Noninvasive Glucose Monitoring With Optical Heterodyne Polarimetry in a Range of 50 mg/dl ^ 100 mg/dl

Abstract

An amplitude sensitive optical heterodyne polarimeter was setup in order to monitor noninvasively the aqueous glucose concentration in rabbit's eye. A range of the blood glucose from 35 mg/dl to 135mg/dl was measured in vivo by biological glucose assay (BGA), while the optical rotation of the aqueous glucose was measured by a polarimeter simultaneously. The experimental results showed the consistence between these two independent measurements. There was no time delay between the blood glucose and the aqueous glucose when the blood glucose was descending after the insulin was injected It was ill contract to a 10 minutes time delay when the blood glucose wvas ascending. The detection sensitivity of the polarimeter was 4 mg/dl in the measurement. Key %ords : heterodyne polarinieter. glucose noninvasive

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2000
Accession Number
ADP011237

Entities

People

  • Chien Chou
  • Chien-yuan Han
  • Pei-chin Tu
  • Wei-hsiung Wang

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Analyzers
  • Contrast
  • Detection
  • Frequency
  • Intensity
  • Laser Beams
  • Lasers
  • Measurement
  • Measuring Instruments
  • Membranes
  • Monitoring
  • New Zealand
  • Optical Detection
  • Polarimeters
  • Radiation
  • Rotation
  • Sensitivity

Fields of Study

  • Physics

Readers

  • Analytical Chemistry
  • Immunology
  • Medical Imaging.