Computational Fluid Dynamics Models of Molecularly Imprinted Materials in Microfluidic Channels

Abstract

Current research will lead to rapid-prototyping of chemical sensors that utilize microfabricated molecularly imprinted (MI) materials. CFD/CAD software may be used to model flow and chemical binding properties of Ml materials in microfluidic channels. Use of this type of software expedites results when changes in properties are made. The surface concentration of bound analyze on a monolithic molecularly imprinted polymer (MIP) within microfluidic channels can be modeled using its experimental binding kinetics. The time necessary to reach a detection limit is calculated and optimized as a function of flow parameters. In this report, we discuss the unique issues associated with the modeling of chemical sensors that utilize MI materials.

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Document Details

Document Type
Technical Report
Publication Date
Apr 05, 2002
Accession Number
ADP013606

Entities

People

  • Cindy K. Webber
  • M. J. Roberts

Organizations

  • Naval Air Warfare Center

Tags

DTIC Thesaurus Topics

  • California
  • Chemical Reactions
  • Computational Fluid Dynamics
  • Computer-Aided Design
  • Detectors
  • Dynamics
  • Engineering
  • Engineers
  • Fabrication
  • Flow
  • Fluid Dynamics
  • Fluid Flow
  • Materials
  • Models
  • Optical Detectors
  • Software Prototyping
  • Surface Roughness

Fields of Study

  • Chemistry

Readers

  • Distributed Systems and Data Platform Development
  • Fluid Dynamics.
  • Nanocomposite Materials Science