The Stability and Oxidation Resistance of Iron- and Cobalt-Based Magnetic Nanoparticle Fluids Fabricated by Inert-Gas Condensation
Abstract
Magnetic nanoparticle fluids have numerous biomedical applications, including magnetic imaging, drug delivery, and hyperthermia treatment for cancer. Ideal magnetic nanoparticle fluids have well-separated, biocompatible nanoparticles with a small size distribution that form a stable colloid. We have combined inert-gas condensation, which produces nanoparticles with low polydispersity, with deposition directly into a surfactant-laden fluid to prevent agglomeration. Iron, cobalt, and iron-nitride nanoparticle fluids fabricated using inert-gas condensation have with mean particle sizes from 5-50 nm and remain stable over long periods of time. Iron and cobalt nanoparticles oxidize on exposure to air, with oxidation and corrosion resistant, while retaining the same high degree of colloidal stability. Magnetic properties vary depending on the nanoparticle size and material, but can be varied from superparamagnetic to ferromagnetic with coercivities on the order of 1000 Oe. In addition to future biomedical applications, inert-gas condensation into fluids offers the opportunity to study interparticle interactions over a broad range of intrinsic materials parameters and interparticle separations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2005
- Accession Number
- ADP019745
Entities
People
- Diandra Leslie-pelecky
- Jeffrey E. Shield
- Michelle A. Strand
- Nguyen H. Hai
- Raymond Lemoine
- Shaina Remboldt
- Steve Wignall
Organizations
- University of Nebraska–Lincoln