Bio-integrated sensor patch comprising semiconducting silicon nanoneedles for intratissue and intracellular recording
Abstract
The ability to efficiently record or transfer information from/to biological systems such ascells and tissues is limited by which current techniques suffer from the low temporal andspatial resolutions. This collaborative research aims to develop a mechanically flexible andelastic sensor patch that is capable of intimately interfacing with the curvilinear surface ofbiological systems in a minimally invasive manner. Uniquely, the sensor patch will include avertically ordered array of semiconducting silicon nanoneedles to serve as the active sensingelement that can measure high-level of electrophysiological signals at the nanoscale. Theexpected outcome will provide a first-of-its-kind mechanically compliant nanoprobe based ona vertically ordered array of silicon nanoneedles for efficient intracellular and intratissuerecordings. The functionalities of the proposed nanoprobe platform can be potentiallyextendable to many other applications such as nanoscale electrical stimulations, on-demandlocalized drug deliveries, and optogenetic light-emitting diodes by modulating the embeddedelectronic properties and/or compositions of the nanoneedles.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Sep 19, 2018
- Source ID
- FA23861814071
Entities
People
- Chi Hwan Lee
Organizations
- Air Force Office of Scientific Research
- United States Air Force
- University of Virginia