Mitochondrial Biohybrid Electron-Transport Chains Supported on Functionalized Graphene Oxide
Abstract
To understand mitochondrial systems well enough to assemble a hybrid electron transport chain on a graphene oxide backbone tagged with dehydrogenases and His-tagged subunits. Further intentions are to be able to stabilize the enzymatic activity, alter the enzymatic activity via magnetic and electronic means as well as "tune" the graphene oxide to more appropriately mimic the natural mitochondrial electron transfer chain. The ultimate intent of this project is to put together a system that is capable of reacting as efficiently as photosynthesis (specifically photosystems I&II). Given the basic physical chemical characteristics of the photosynthetic and mitochondrial electron transport chains, it is possible to envision that chemical, electric, magnetic, and radiative stimuli can induce changes in their biochemical activity and affect their energy efficiency.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jul 15, 2016
- Source ID
- FA95501610279
Entities
People
- Michele Vittadello
Organizations
- Air Force Office of Scientific Research
- Research Foundation of The City University of New York
- United States Air Force