Laboratory Automation For Rapid, Cell-Free Design Space Exploration And Robustness Analysis Of Biomolecular Circuits

Abstract

To provide the laboratory automation capabilities required to implement this approach, wepropose to purchase nanoliter scale liquid handling system that can create complex assays for bothdesign space exploration and robustness analysis. The Echo 525 liquid handler, sold by Labcyte,provides this capability by using acoustic waves to transfer 25 nl droplets from a 384 well microplateto a 384 or 1536 well microplate, with total volume of up to 10 l per well. The system is thuscapable of rapidly creating up to 1536 experiments in which the components of each experiment(well) can consist of any combination of up to 384 reagents, mixed in dierent proportions.

Document Details

Document Type
DoD Grant Award
Publication Date
Dec 05, 2016
Source ID
FA95501610338

Entities

People

  • Richard M. Murray

Organizations

  • Air Force Office of Scientific Research
  • California Institute of Technology
  • United States Air Force

Tags

Readers

  • Analytical Chemistry
  • Distributed Systems and Data Platform Development
  • Research Science/Academic Research

Technology Areas

  • Space
  • Space - Hall-Effect Thruster