Macromolecular Modeling of Biomimetic Assembly
Abstract
We propose to perform statistical mechanics polymer theory and multiscale molecular modelingon four major areas: (1) Aggregation mechanism of similarly charged macromolecules and in particular DNA in aqueous solutions containing monovalent salt, (2) Assembly and kinetics of proteins and biomimetic macromolecules in the context of collagen, silk, and prefoldin, (3) Electrostatic complexation and coacervation, in the context of phase diagrams and coacervate-like materials, and (4) Dissolution and assembly of silk and cellulose in ionic liquids. The proposed work is complementary to the ongoing eorts in the current program. Our work will be conducted in synergistic cooperation between us and several experimental groups. In addition, we will continue to provide support to the program participants with our static and dynamic light scattering expertise.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jul 28, 2017
- Source ID
- FA95501710160
Entities
People
- Murugappan Muthukumar
Organizations
- Air Force Office of Scientific Research
- United States Air Force
- University of Massachusetts Amherst