DNA Nanotechnology for Single-Molecule Monitoring of Target-Analyte Interactions

Abstract

Advances in nanofabrication technologies and nanoscale assembly strategies have opened up possibilities in the development of novel platforms for the fundamental understanding of bio-molecular recognition processes with single-molecule resolution, and for the detection of biological agents with single-molecule sensitivity. The ability to investigate and sense target-analyte interactions with single-molecule control could permit the fabrication of biochips offering unmatched sensitivity, smaller test sample volumes, and high throughput analysis through the monitoring of distinct biorecognition events in parallel and on a single chip. This holds great potential for applications in a wide variety of areas.

Document Details

Document Type
DoD Grant Award
Publication Date
May 02, 2017
Source ID
FA95501710179

Entities

People

  • Matteo Palma

Organizations

  • Air Force Office of Scientific Research
  • Queen Mary University of London
  • United States Air Force

Tags

Fields of Study

  • Chemistry

Readers

  • Nanoscale Plasmonic Nanotechnology

Technology Areas

  • Biotechnology