Advanced Optical Technologies for Defense Trauma and Critical Care
Abstract
This is an integrated proposal of six projects that individually, and combined employ opticalbased technologies specifically for the purpose of advancing combat casualty care of woundedwarfighters, as mandated by the Department of Defense. All of the projects of this proposal focuson aspects of trauma and critical care assessment and management, and have defineddeliverables in terms of a device and/or procedure that addresses JFHP capability gaps. Projects1 and 2 focus on Functional Imaging: The goal of Project 1 is the development and evaluationof technologies for comprehensive real time quantitative measurement of tissue lactic acid, pO2,oxy- and deoxy-hemoglobin, and cytochrome c oxidase redox state, to develop non-invasivemethods for detecting acute dehydration in active soldiers, and development of a miniaturized,wearable Diffuse Optical Spectroscopy device that will enable these applications. Project 3’sgoal is wide-field functional imaging for assessment of burns and wound healing. Projects 4 and5 are focused on Structural Imaging: The goal of Project 4 is the development of a high-speedlong-range Fourier domain OCT system for imaging inhalation airway injury and respiratoryepithelial cilia function, and Project 5 will develop non-linear optical imaging technologies forin-vivo detection and monitoring the treatment of bacterial biofilms in wounds. Project 6 willcontinue studies to determine the cellular pathways important to the repair of traumatic brain andspinal cord injury.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- May 02, 2017
- Source ID
- FA95501710193
Entities
People
- Michael W. Berns
Organizations
- Air Force Office of Scientific Research
- United States Air Force
- University of California, Irvine