Enhancing Biological Performance and Protection: Occurrence, Mechanisms and Applications
Abstract
This proposal is designed to extend previous U.S. Air Force funded research on the occurrence, frequency, mechanisms, biomedical and other scientific and regulatory implications of the hormetic dose response. The proposed work will continue the development and expansion of the hormesis database, provide critical assessments within each of five general areas (1) hormesis-adaptive response in the field of wound healing; (2) hormesis in stem (NIR) cell function along with biological, biomedical and therapeutic applications; (3) hormetic effects of non ionizing radiation (i.e., laser light, radio frequency radiation and magnetic fields); (4) preand post conditioning hormesis; and (5) the area of hormetic and epigenetics, including transgenerational hormesis. The proposal will also provide scientific leadership by organizing and conducting an annual conference on scientific progress in the assessment of hormesis and two Air Force Workshops on high profile hormesis topics such as epigenetics and translational hormesis and how they affect biological enhancement and protection. The proposal also includes overseeing publication of expert panel peer reviewed papers from these workshops in the journal Dose Response.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jan 14, 2022
- Source ID
- FA95501910413
Entities
People
- Edward Calabrese
Organizations
- Air Force Office of Scientific Research
- United States Air Force
- University of Massachusetts Amherst