ADVANCED OPTICAL TECHNOLOGIES FOR DEFENSE TRAUMA AND CRITICAL CARE
Abstract
This is an integrated proposal of eight projects that individually, and combined employ optical based technologies specifically for the purpose of meeting capability gaps in the medical care of wounded warfighters, as identified by the Department of Defense. All of the projects of this proposal focus on aspects of trauma and critical care assessment and management, and have defined deliverables in terms of a device and/or procedure that addresses JFHP capability gaps. Project 1 will develop a non-invasive wearable sensor to provide continuous physiologic information in order to optimize stabilization and treatment strategies during and beyond the Golden Hour of battlefield injury. Project 2 will develop wearable hemodynamic and metabolic sensors for critical care assessment and monitoring of lactate and other hemodynamic markers. Project 3’s goal is to develop a flow-enhanced modification of pulse oximetry for improved performance in far-forward field conditions. Project 4 will develop a durable, compact blood coagulation analyzer for real-time coagulation assessment. Project 5 will further develop, enhance, and expand our patented and now commercially available tissue viability surgical camera to quantitatively and non-invasively assess directed energy burns, thermal burns over large surface areas, and assess burn interventions using wide-field functional imaging. Project 6 will expand the development of functional OCT to add airway compliance and ciliary function capabilities to the characterization of inhalation airway injury. The goal of Project 7 is the further development and validation of a hand-held, point-of-care wound infection and biofilm imaging device. Project 8 will focus on developing an in vitro assay system for structural and functional mechanisms of traumatic brain (TBI) and spinal cord injury. Projects 1, 2, 4, 5 and 6 involve collaborative efforts with research groups at the US Army Institute of Surgical Research (USAISR). In addition to the eight projects, this proposal also includes funds for administrative core support that provides service to all of the individual projects. All of the projects involve filing of intellectual property rights for patent protection, and/or a commercialization plan. The unique translational design of the Beckman Laser Institute and Medical Clinic, including its Photonic Incubator, along with resources and support of the UCI Beall Applied Innovation for commercialization of devices is ideally suited for this program.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Aug 12, 2021
- Source ID
- FA95502010052
Entities
People
- Michael W. Berns
Organizations
- Air Force Office of Scientific Research
- Office of the Secretary of Defense
- University of California, Irvine