EXPLORING NEW BIOPHYSICAL PROPERTIES WITH QUANTUM ENTANGLEMENT
Abstract
In this proposed project with the Air force Office of Scientific Research we will investigate the mechanism of excitations of proteins in living cells with nonclassical (entangled) light. The goal of this project is to develop new biological and chemical structure-function relationships in biological cells, which result from the interaction of electronic states of organic matter with quantum entangled light. Specifically, we will investigate the nonlinear quantum optical effects of endogenous proteins using entangled two-photon absorption and fluorescence measurements (ETPA) as well as theoretical modeling developed in the PI’s research laboratory. Within this Project we will obtain images of living healthy and cancer cells will be obtained with an entangled two-photon microscope in the PI’s laboratory, which will be upgraded specifically for investigating biological cells. Specific selection rules for the entangled two-photon excitation and imaging will be defined in biological systems and in living cells. Experiments and modelling will be directed at the possibility of using quantum entangled light to control photochemical reactions in biological systems. In order to develop new structure-function relationships the PI’s lab will investigate the photochemical processes originating from the intermediate (virtual) level after ETPA excitation and compare with classical analogs. We will carry out investigations of the biophotonic emission in living cells under different stress. The photon statistics of the emitted biophotons will be measured and modelled. The deliverables of this project will be new structurefunction relationships regarding the interaction of quantum light with proteins in living cells, the possibility to control photochemical processes in cells thru the interactions of entangled light with their intermediate (virtual) states, and understanding of the statistics of biophotonic emission.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Aug 12, 2021
- Source ID
- FA95502010380
Entities
People
- Theodore Goodson, III
Organizations
- Air Force Office of Scientific Research
- Board of Regents of the University of Michigan
- United States Air Force