DNA-Programmed Assembly of Hierarchical Mesoporous Materials
Abstract
DNA is one of the most programmable assembly tools used for nanomaterials synthesis. However, DNA nanostructures are typically only stable in a narrow range of conditions, have difficulty dictating structural features larger than approximately 100 nm, and exhibit a limited set of physical properties. Fundamental research is thus required to understand how DNA assembly can be paired with other fabrication techniques to generate hierarchical structures across the nano- to macroscopic scales, and to transform these structures into a more chemically diverse and robust set of materials. Here we will address these challenges by using DNA to assemble mesoporous nanoparticle superlattices on patterned substrates, followed by chemical encapsulation of the ordered arrays in photocatalytic coatings. Aim 1- Establish basic principles of DNA-programmed interfacial crystallization. We will examine how DNA design parameters affect nanoparticle crystal growth into faceted architectures, and establish a highly programmable model system to develop generalizable design principles for crystal growth. Aim 2- Assemble superlattices at patterned interfaces to dictate crystal growth. We will investigate how growth of DNA-assembled crystallites on lithographically defined patterns enables biotemplated materials with controlled nano- to macroscale architectures, positioned at predetermined sites on a surface. Aim 3- Templated growth of mesoporous materials around a PAE superlattice. We will use DNA strands in the assembled materials as scaffolds to grow mesoporous ceramics. We will combine this DNA-enabled tailorability in pore size, shape, and connectivity with the ability to specifically position the lattices across a surface to investigate how mesopore path structure affects catalytic activity. These studies will lead to new fundamental principles in crystal formation and structure-property behaviors (e.g. diffusion rates, catalytic efficiency) in mesoporous materials. Defense relevant applications of these bioprogrammed mesoporous structures include high surface area catalysts for chemical production, and porous media for sensing and decomposition of dangerous chemicals.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Feb 29, 2024
- Source ID
- FA95502310210
Entities
People
- Robert J Macfarlane
Organizations
- Air Force Office of Scientific Research
- Massachusetts Institute of Technology
- United States Air Force