INVESTIGATION OF THE PHOTOTHERMAL EFFECT DURING THE INTERACTION OF ELECTROMAGNETIC RADIATION WITH BIOLOGICAL TISSUE
Abstract
This project explores light-induced thermal damage and its effects on cell death and tissue integrity, focusing on rat liver cells. Employing in vitro and in vivo models, the study investigates temperature thresholds for damage, thermally-induced apoptosis, and the correlation between temperature and mitochondrial efficiency. It aims to reveal the interplay between heat generation from radiation absorption and its biological impacts. The outcomes should offer critical insights into phototherapy-related thermal effects and the healing process in burns, potentially improving therapeutic strategies and patient outcomes.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Mar 07, 2024
- Source ID
- FA95502310660
Entities
People
- Vanderlei Bagnato
Organizations
- Air Force Office of Scientific Research
- São Carlos Institute of Physics at the University of São Paulo
- United States Air Force