Advanced Optical Technologies for Defense Trauma and Critical Care for military medical photonics
Abstract
This is an integrated proposal of eight projects that employ optical based technologies for the purpose of meeting DHA identified capability gaps in the medical and-or surgical care of wounded warfighters. Project 1 will advance Wide Field Imaging Technology (WiFI) as a noninvasive tool for rapid characterization, assessment, and mapping of soft tissue trauma, thermal burns, and injury by directed energy. Project 2 will further develop a wearable continuous lactate monitor through TRL 4 to reduce battlefield morbidity and mortality. Project 3 will make a significant advancement in pulse oximetry by creating a wearable sensor that directly measures arterial pulsatile blood flow and oxygen delivery while reducing inherent artifacts related to temperature and motion. Project 4 will develop a field-deployable compact blood coagulation analyzer for real-time coagulation monitoring at point of care. Project 5 will evaluate three platform technologies - a) wearable lactate, pH and pressure sensor; b) high frequency ultrasound and photoacoustic tomography; and c) diffuse optical spectroscopy for early detection of compartment syndrome in support of on-going studies at USA-ISR. Project 6 will further develop a portable, functional OCT system to assess inhalation airway injury and monitor pulmonary effects of fluid resuscitation. The goal of Project 7 is to develop a field-deployable dual wavelength surgical laser platform and handpiece capable of performing bloodless tissue debridement of battlefield injuries. Project 8 will focus on identifying biomarkers and molecular signatures of TBI in both cells and an animal model and will develop a retinal imaging system to detect TBI biomarkers. Projects 1, 2, 4, 5, 6 and 8 involve collaborative efforts with research groups at the US Army Institute of Surgical Research (USA-ISR) or the Autonomous Reanimation and Evacuation (AREVA) Research program. All of the projects involve filing of intellectual property rights for patent protection and a commercialization plan.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Mar 14, 2024
- Source ID
- FA95502310685
Entities
People
- Thomas Milner
Organizations
- Air Force Office of Scientific Research
- United States Air Force
- University of California, Irvine