An Integrated Technology Platform with Photoelectrical and Electromagnetic (EM) Stimulator Arrays with Tunable Frequency and Contactless Quantum Spintronic Sensor Array for Understanding of Neuromorph
Abstract
This proposed project aims at the construction of an advanced stimulation-sensing platform to discover and understand new biophysics properties; the focus throughout this study will be on fundamental interactions occurring at or below cellular scale. In order to elucidate the nature of these interactions, we will leverage devices and testing platforms with multiple levels of frontier techniques. These will include magnetic and spintronic (U Minnesota), photoelectronic (Tor Vergata University) as well as prediction and deep-learning (U Minnesota) that will be synergistically employed to visualize the underlying dynamic neuromorphic framework of the natural biology. Hierarchic research activities will focus on multiple dimensions, from molecular, cells, tissue and interface levels to specifically investigate optic nerve activation pathways using integrated technologies to in vitro scenarios This will be in conjunction with the aim of technical improvement, progress that can broaden the toolbox and boundary of biophysical research. We will answer the question- How does the vision system responds to the electromagnetic field with different frequencies and intensities? An understanding on this will support precise visual augmentation and protection of pilots in extreme environments including strong electromagnetic (EM) and light fields. Objectives- The core objectives for this research proposal will be broken down into three main areas with a strategic feedback loop to inform each other, focusing on fundamental interactions occurring at or below cellular scale- Modulation of Vision; Neural Response; Integrated Device Platform for Optical and EM Triggering and Spintronic Sensing; Computing and modeling Collaboration with other PIs and teams for EM Triggering and Optical Sensing- we will advance a new frontier and work with collaborators by using magnetically and optically active molecular units that can be functionalized to connect to or be incorporated inside the living cells, rather than having to interface these onto polymer films. By anchoring or incorporating the optoelectronic element to or inside the cell itself, the team can provide the cells with new opto- electrical capabilities, which they previously lacked. The team has obtained a strong support from Prof Muayyad Al-Ubaidi, from the University of Houston, who pioneered the 661W photoreceptor- like cells line. The team has engaged a discussion for the collaboration with Prof. Norbert Linz from the Universitat zu Lubeck to evaluate the stress effects on the vision cells through the laser cell interaction. Broad impacts- This proposal leverages the most frontier simulative and characterization techniques developed this international team, to build a new stimulation-sensing- deciphering protocol for biophysical research. We envision the success of this project will provide new opportunities to develop novel materials and devices for stimulation and sensing, a research platform for discoveries of new biophysics and-or fundamental models in nature, furthering the interdisciplinary development and international collaboration as well as knowledge-expertise exchange and re-generation and comprehensive training of higher-skilled workforce. Student Training- This international collaboration will also be cultivated by international student exchange between the University of Minnesota and Tor Vergata University of Rome.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Feb 06, 2025
- Source ID
- FA95502410320
Entities
People
- Jian-Ping Wang
Organizations
- Air Force Office of Scientific Research
- Regents of the University of Minnesota
- United States Air Force