Biochemical and Mechanical Stressors on Warfighter Immunity- On Earth and Beyond
Abstract
Warfighters face unique challenges in health maintenance due to exposure to hostile environments and stressful situations. This research aims to understand how these situational stressors impact the immune system of warfighters, with a focus on key immune cells involved in responding to damage and infection. Using innovative cell-based health avatars, we will simulate warfighter stressors in the lab and study their effects on immune cell behavior and function to uncover drivers of immune dysfunction. We will then test pharmacological interventions to target these mechanisms and restore immune function, and to inform future preventative care and interventional strategies. By gaining insights into the health hazards faced by combat forces, we aim to enhance mission capability and success, and to promote warfighter health and well-being.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Feb 06, 2025
- Source ID
- FA95502410456
Entities
People
- Meenal Datta
Organizations
- Air Force Office of Scientific Research
- United States Air Force
- University of Notre Dame