Comprehensive Research for Detecting Origin and Distribution of Peste des Petits Ruminants
Abstract
Peste des petits ruminants is a highly contagious and often fatal disease of small ruminants with significant economic, food security and livelihood impacts. The disease is caused by a morbillivirus closely related to rinderpest virus. Clinically, PPR resembles pneumonic pasteurellosis, contagious caprine pleuropneumonia, sheep and goat pox, contagious ecthyma, bluetongue, and foot-and-mouth disease. In January, 2016 PPR was detected in Georgia. Up to present the origin of virus, age relationship of affected ruminants and distribution of PPRV in Georgia remains unclear. Due to the nature of PPR, and breeding practices in the country, reemerging of the disease in Georgia is highly likely. Thus, we propose to establish a PPRV survey in Georgia by collecting samples from small ruminants in different regions of the country that will enable the identification of areas at high risk of the disease. Detected PPRV will be fully sequenced and sequences will be compared with those obtained from previously detected viruses with vaccine viruses and with viruses detected elsewhere in the region. Overall, the work will ensure effective surveillance of PPR and accurate distinction from look-alike diseases.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Dec 28, 2020
- Source ID
- HDTRA11810053
Entities
People
- Nino Vepkhvadze
Organizations
- Defense Threat Reduction Agency