Feasibility and Development of a Carbon Nanotube FET Based-IVD for Acute Opioid Exposure

Abstract

The central objective of this proposal is the development of three parallel strategies to address portable ultralow detection of opioids. Automation of carbon nanotube-based sensor manufacture will be used to rapidly develop specific biomolecule, machine learning sensor array, and molecularly imprinted polymers. Complementary strategies will enable large datasets to be used as a comparison against traditional analytical techniques, as well as fundamental understanding about differential physical behavior of analytes with specific receptors. Primary output will be an addition to the ChemDx portable prototype device equipped with a suite of selective chemistry to allow electrochemical detection of opioids in human finger-stick blood samples.

Document Details

Document Type
DoD Grant Award
Publication Date
Jun 14, 2022
Source ID
HDTRA12110009

Entities

People

  • Alexander Star

Organizations

  • Defense Threat Reduction Agency
  • University of Pittsburgh

Tags

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Nanocomposite Materials Science
  • Neurotrauma and Rehabilitation Medicine.

Technology Areas

  • AI & ML