Monkeypox Threat Reduction Network

Abstract

In order to prevent the entry of known and novel pathogens into the USA, a sustainable biosurveillance system is needed in DTRA Direct Engagement Countries (DECs) to detect and respond to cases of monkeypox (MPX), viral hemorrhagic fevers/Ebolavirus, coronaviruses, and other viral pathogens globally. The DTRA DECs highlighted in this proposal (excluding Nigeria) have underprepared surveillance systems, in part because they are not conducting surveillance activities for MPX and partially due to challenges with diagnostic capacity, lower caseload and less experiences. The Democratic Republic of the Congo (DRC) has developed regional expertise in MPX because of the high number of cases in various parts of the country. There is the opportunity to use the DRC as a training center in sentinel sites for MPX detection for DTRA DECs. This project has 5 aims, 4 of which have research and capacity building components, while1 focuses on the development of the regional training center based on sentinel sites for MPX surveillance in the DRC. Use of sentinel training sites in the DRC for MPX case detection, outbreak response, surveillance and laboratory diagnostics could play a role in reducing the threat to the USA from deadly viral pathogens with Weapon of Mass Destruction potential. In order to prevent the entry of known and novel pathogens into the USA, a sustainable biosurveillance system is needed in DTRA Direct Engagement Countries (DECs) to detect and respond to cases of monkeypox (MPX), viral hemorrhagic fevers/Ebolavirus, coronaviruses, and other viral pathogens globally. The DTRA DECs highlighted in this proposal (excluding Nigeria) have underprepared surveillance systems, in part because they are not conducting surveillance activities for MPX and partially due to challenges with diagnostic capacity, lower caseload and less experiences. The Democratic Republic of the Congo (DRC) has developed regional expertise in MPX because of the high number of cases in various parts of the country. There is the opportunity to use the DRC as a training center in sentinel sites for MPX detection for DTRA DECs. This project has 5 aims, 4 of which have research and capacity building components, while1 focuses on the development of the regional training center based on sentinel sites for MPX surveillance in the DRC. Use of sentinel training sites in the DRC for MPX case detection, outbreak response, surveillance and laboratory diagnostics could play a role in reducing the threat to the USA from deadly viral pathogens with Weapon of Mass Destruction potential.

Document Details

Document Type
DoD Grant Award
Publication Date
Oct 13, 2021
Source ID
HDTRA12110040

Entities

People

  • Anne Walsh

Organizations

  • Defense Threat Reduction Agency
  • University of California

Tags

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Tactical Satellite Communications Systems Engineering.
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology