Genomics of Vitamin D Supplementation and Warfighter Nutritional Resilience
Abstract
The increasing awareness of vitamin D deficiency as a public health epidemic, and the knowledge gap regarding the clinical and physiologic relevance of this, warrant scientific investigation to better understand skeletal and non-skeletal effects of this ubiquitous steroid hormone. A genomics-based approach will target identified candidate genes and search for variants that may explain the response observed in biomarkers and symptoms when deficient individuals are repleted. The long-term objective of this study is to translate findings from next-generation sequencing (NGS) technology into clinically meaningful data regarding vitamin D supplementation for Service Members (SM) who may be at risk for musculoskeletal disorders and immune dysfunction that impacts physical performance and military readiness.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Oct 18, 2018
- Source ID
- HU0001151TS05
Entities
People
- Mary S. McCarthy
Organizations
- Geneva Foundation
- Uniformed Services University of the Health Sciences