Evaluation of the Validity of Cholesterol as a Biomarker for Suicide in Veterans
Abstract
Previous research has indicated that cholesterol may be a valid biomarker for suicide. Serum cholesterol levels below 160 mg/dl decreases the brain cell membrane cholesterol, lowers the lipid microviscosity, and reduces the the availability of serotonin receptors on the membrane surface. This results in reduced serotonin uptake into brain cells, and may increase self-directed aggression and suicide in susceptible individuals. Research will take place at Coatesville VAMC. Data on veterans who have been admitted for suicide ideation, suicide attempt, and veterans who have completed suicide between 2009 and 2014 will collected (population N = 375). Once a veteran has been identified in the suicide prevention coordinator s database, all visits to the facility will be collected. The foremost variable is the cholesterol level and whether admission was the result of an ideation, attempt, or a completed suicide. Additional data will include but not limited to the method intended or used for the suicide, diagnoses and medications.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Oct 18, 2018
- Source ID
- HU0001151TS13
Entities
People
- Charles Reuter
Organizations
- Rutgers University
- Uniformed Services University of the Health Sciences