MEDICAL CHEMICAL DEFENSE (ACD&P)

Abstract

This project funds Advanced Component Development and Prototypes (ACD&P) of countermeasures for chemical agents including life support equipment, diagnostic equipment, prophylactic and therapeutic drugs, and individual/casualty decontamination compounds. A system of medical defense against chemical agents is required to provide protection, to sustain performance in a chemical environment, and to provide for self-aid/buddy-aid and medical treatment of chemical casualties. Fielding of prophylactic and therapeutic drugs requires Food and Drug Administration (FDA) approval. Multiple long-term studies are required to obtain FDA approval resulting in longer program timelines and greater program cost than other non-pharmaceutical product programs. Efficacy testing of most candidate drugs against chemical warfare (CW) agents cannot be conducted in humans; therefore, animal surrogate models must be developed. The program currently funds the: (1) Bioscavenger Increment 2 (BSCAV Inc. 2), which will be used as a prophylaxis against nerve agents; (2) Inhalational Atropine (IA), which will be used to treat continuing nerve agent induced effects after the patient has been evacuated to a medical treatment facility; and (3) Improved Nerve Agent Treatment System (INATS), which will be used as a treatment for nerve agent intoxication to include new indications for Pyridostigmine Bromide (PB) that will be integrated with current therapeutic regimens. Time Temperature Indicators (TTI), Item Unique Identification (IUID), and Radio-Frequency Identification (RFID) will be part of the development effort for incorporation on all medical countermeasures being developed by CBMS-MITS. A TTI is a human readable tab that will provide the Warfighter immediate knowledge if the product is still useable or not. IUID and RFID labels placed on the product will improve inventory management and strategic purchasing, and enable reliable visibility, and capability-based operational readiness.

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Document Details

Document Type
Project
Publication Date
Oct 01, 2011
Source ID
MC4_0603884BP_4_0400_PB_2011

Tags

Fields of Study

  • Medicine

Readers

  • Logistics and Supply Chain Management.
  • Military Science and Technology Research and Modernization.
  • Neurotoxicology

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