Medical Chemical Defense (Op Sys Dev)
Abstract
This project provides for the upgrade and modernization of fielded medical nerve agent treatment system that contribute to the layered medical defenses against chemical warfare agent threats facing U.S. Forces in the field. The effort included in this project are: (1) Improved Nerve Agent Treatment System (INATS) (2) Improved Nerve Agent Treatment System Centrally Acting (INATS CA) (3) Alternative Autoinjector Manufacturer Capability (AUTOINJ) (1) INATS - Soman Nerve Agent Pre-Treatment Pyridostigmine (SNAPP) is a modernization effort for Pyridostigmine Bromide (PB) requirements from the joint service users for the Food and Drug Administration (FDA) approved SNAPP product. (2) INATS-CA advanced development provides a centrally-acting anticholinergic agent to increase survivability and decrease morbidity after exposure to toxic nerve agent threats. Scopolamine was selected for development after an extensive analysis of alternatives and review of data by the Science and Technology community. Added to the currently fielded system, the INATS-CA program will improve overall medical outcomes and will be utilized as both a vial for use at definitive care and a stand-alone auto-injector for use in the field. (3) AUTOINJ consists of investigating an FDA approved alternative source(s), beyond the single current Department of Defense (DoD) source, for autoinjectors that deliver DoD nerve agent antidote and treatment capabilities to the warfighter; mitigates capability fielding and operational readiness risks. This resulted from the manufacturing and quality issues for the fielded Antidote Treatment Nerve Agent Auto-injector (ATNAA) product, the oxime (2-PAM) and atropine in a dual chambered autoinjector. This program augments legacy autoinjectors, ATNAA, 2-PAM, and CANA by providing alternative commercial sources which include Dual Drug Delivery Device (D4), the atropine autoinjector, and anti-convulsant autoinjector.
Document Details
- Document Type
- Project
- Publication Date
- Oct 01, 2021
- Source ID
- MC7_0607384BP_7_0400_PB_2021
Related Documents
- Root: CHEMICAL/BIOLOGICAL DEFENSE (OP SYS DEV)
- Child Accomplishment: 1) Alternative Autoinjector Manufacturer Capability (AUTOINJ)
- Child Accomplishment: 2) INATS
- Child Accomplishment: 3) INATS - CA
- Child Cost Item: b5842839dbac06ad6287b5e9c3a438e9
- Child Cost Item: 43abfc0564a856e27b3f7bc8ced0c151
- Child Cost Item: 7a94db9687772007b29159d297e7469e
- Child Cost Item: b42252b2a7fb72562c5f819dfea43958
- Child Cost Item: dea8f4b50c2b1d9c29076c9c378d9c12