Mitigate (Op Sys Dev)

Abstract

The Mitigate Operational System Development Project provides the Joint Force continued readiness of fielded personnel and materiel contamination mitigation and chemical agent therapeutic capabilities and provides size, weight and power improvements to reduce logistical burden on the Warfighter. Efforts included in this Project are: (1)Improved Nerve Agent Treatment System Centrally Acting (INATS CA), and (2)Modernization Protection Decontamination (MODPROT DE) INATS CA will develop the centrally-acting anticholinergic, scopolamine, to increase survivability and decrease morbidity following exposure to toxic nerve agents. When added to currently fielded nerve agent treatments, scopolamine will improve overall medical outcomes and will be available in both a vial for use at definitive care, and in an autoinjector for use in the field. INATS CA includes modernization of Soman Nerve Agent Pretreatment Pyridostigmine (SNAPP; pyridostigmine bromide [PB] tablets). In FY23, INATS CA continues studies on the Food and Drug Administration (FDA)-approved SNAPP, a medical pretreatment against nerve agent poisoning to upgrade its joint service utility and ensure its continued safety and efficacy. Also in FY23, the INATS CA program will submit to the FDA for approval, documents supporting sustained release PB tablets in blister packs. These tablets will provide a single tablet per day dose alternative to the current SNAPP dosing regimen for the pretreatment against soman nerve agent poisoning. MODPROT DE addresses obsolescence and technical data concerns, beginning with the M26 Joint Services Transportable Decontamination System-Small Scale (JSTDS-SS) through validation and verification of Technical Manual (TM) changes as well as technical data for spare and repair parts; the M12A1 Power Driven Decontamination Apparatus (PDDA) by updating technical references and performing the necessary validation and verification before publishing an updated TM. In FY23, MODPROT DE will continue to update technical data for spares and repair parts for M26 JSTDS-SS Technical Data Package (TDP) and continue to update technical references and validation/verification efforts for M12A1 PDDA TM.

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Document Details

Document Type
Project
Publication Date
Oct 01, 2023
Source ID
MT7_0607384BP_7_0400_PB_2023

Tags

Fields of Study

  • Medicine

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Neurotoxicology

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