Self-replicating DNA Nanostructures
Abstract
The proposed effort has three specific aims: 1. Design and construct complex DNA origami nanostructures that are folded from a solitary, long, single-strand of DNA without short staple DNA strands so that the DNA nanostructures are accessible to DNA polymerases and can be cloned into plasmids for in vivo replication. 2. Develop methods to clone or replicate the structures. 3. Develop strategies to evolve functional replicable DNA nanostructures.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Aug 08, 2016
- Source ID
- N000141512689
Entities
People
- Hao Yan
Organizations
- Arizona State University
- Office of Naval Research
- United States Navy