This grant is a continuation of N00014-13-1-0552 Paining Metabolic Landscapes using 21st century bacterial genetics and synthetic biology

Abstract

The proposal focuses on new methods for discovering unusual microbial metabolisms, specifically focusing on mechanisms of electron transport into microbial catalysts using electrical current. Two model bacterial systems (Shewanella oneidensis and Marinobacter) will be employed for the study which will attempt to domesticate an obligate iron oxidizing bacterium using synthetic biology. Three objectives are proposed that address the need for new high-throughput methods for discovery of unusual microbial metabolisms, with a particular emphasis on novel electron transport pathways related to electrode oxidation and reduction.

Document Details

Document Type
DoD Grant Award
Publication Date
Jun 03, 2016
Source ID
N000141612183

Entities

People

  • Jeff Gralnick

Organizations

  • Office of Naval Research
  • Regents of the University of Minnesota
  • United States Navy

Tags

Readers

  • Microbial Pathology
  • Nanocomposite Materials Science
  • Systems Analysis and Design

Technology Areas

  • Biotechnology
  • Microelectronics